Trump Launches Genesis Mission AI Initiative

Nov. 25, 2025 /Mpelembe Media/ — The provided text details the inauguration of the “Genesis Mission”, a significant artificial intelligence (AI) initiative launched through an executive order signed by President Donald Trump in November 2025. This federal effort is aimed at dramatically accelerating American AI research, development, and application, particularly in scientific fields, and has been compared to the historical Manhattan Project in its urgency and ambition. The mission intends to leverage vast federal datasets and expand computational resources to create sophisticated AI models, with goals including strengthening national security and accelerating scientific discovery. This initiative builds upon existing frameworks like the National Artificial Intelligence Research Resource (NAIRR) and involves partnerships with key figures and agencies, such as the Department of Energy, to establish essential infrastructure like the “American Science and Security Platform.”

The overarching mission of the Genesis Mission AI initiative is to supercharge American artificial intelligence research, development, and scientific applications, establishing a new federal push to mobilise the federal government’s research and data to create artificial intelligence models.

The order launching the initiative states that the Genesis Mission will achieve several critical goals, including:

Dramatically accelerating scientific discovery.

Strengthening national security.

Securing energy dominance.

Enhancing workforce productivity.

Multiplying the return on taxpayer investment into research and development.

The initiative is viewed as “comparable in urgency and ambition to the Manhattan Project”.

Intended Scope and Mechanism

The intended scope of the Genesis Mission involves building an integrated platform to leverage the world’s largest collection of Federal scientific datasets, which were developed over decades of federal investments.

Key elements of the scope and mechanism include:

Platform Development and Data Harnessing: The mission will build an integrated AI platform to harness these Federal scientific datasets to train scientific foundation models and create AI agents designed to test new hypotheses, automate research workflows, and accelerate scientific breakthroughs.

Centralised Infrastructure: The order charges the Secretary of Energy with establishing a new “American Science and Security Platform”. This platform will centralise the required infrastructure, providing researchers with the necessary computing power and datasets to train AI models.

Data Access: The initiative aims to expand computational resources and increase access to vast federal datasets, specifically targeting barriers to data-sharing by integrating appropriate and available agency data and infrastructure into the Mission. Federal data sets are described as an enviable, but often decentralized and disorganized, gold mine of data.

Real-World Applications: The mission is focused on moving toward impactful, real-world applications, particularly in scientific fields. The order specifies that AI should be applied to practical and critical scientific issues within 270 days. These areas of “science and technology challenges of national importance” include advanced manufacturing and robotics, biotechnology, and nuclear fission and fusion.

The announcement of the Genesis Mission is seen as a strong signal from the U.S. to the world regarding what is possible, potentially transforming the entire scientific, research, and discovery pipeline. The Genesis Mission builds upon the existing National Artificial Intelligence Research Resource (NAIRR), which was created in 2020 to provide a robust national research infrastructure to accelerate AI-powered discovery and innovation.

The President signed the executive order launching the Genesis Mission AI initiative on a Monday afternoon. The date the order was signed was November 24, 2025.

The order is also referred to multiple times in the source material as “Monday’s order” and “Monday’s executive order”.

The individual leading the Genesis Mission AI initiative is Michael Kratsios.

His official titles are assistant to the president for science and technology and director of the Office for Science and Technology Policy.

In this leadership role, Kratsios is specifically charged with the responsibility to integrate “appropriate and available agency data and infrastructure into the Mission”.

Separately, the executive order also charges Secretary of Energy Chris Wright with establishing a new “American Science and Security Platform”, which is meant to centralise the required infrastructure, including computing power and datasets necessary to train AI models. Secretary Wright has previously emphasised the importance of new and creative partnerships for “Winning the AI race”.

The Genesis Mission AI initiative is compared to the Manhattan Project.

Specifically, Monday’s executive order describes the Genesis Mission as “comparable in urgency and ambition to the Manhattan Project”.

The individual who will lead the Genesis Mission effort is Michael Kratsios.

Kratsios holds the titles of assistant to the president for science and technology and director of the Office for Science and Technology Policy.

Furthermore, Monday’s executive order gives Kratsios the specific responsibility to integrate “appropriate and available agency data and infrastructure into the Mission,” addressing the existing barriers to data-sharing within the federal government.

Separately, the order also charges Secretary of Energy Chris Wright with the responsibility of establishing a new “American Science and Security Platform”. This platform is intended to centralise the infrastructure required for the mission, providing researchers with the necessary computing power and datasets to train AI models. Secretary Wright has previously emphasised the importance of new and creative partnerships for “Winning the AI race”.

The executive order signed by President Donald Trump on Monday afternoon launched a new federal effort called the “Genesis Mission”.

The Genesis Mission is a new federal push specifically designed to supercharge American artificial intelligence (AI) research, development, and scientific applications. Its purpose is to mobilise the federal government’s research and data to create artificial intelligence models.

This new effort is described as “comparable in urgency and ambition to the Manhattan Project”.

The initiative involves:

A series of steps to expand computational resources.

Efforts to increase access to vast federal datasets.

A move toward impactful, real-world applications, particularly in scientific fields.

Building an integrated AI platform to harness Federal scientific datasets to train scientific foundation models and create AI agents.

The executive order launching the Genesis Mission AI initiative mandates the establishment of a platform called the “American Science and Security Platform”.

The purpose of the “American Science and Security Platform” is to centralise the infrastructure required for the Genesis Mission. This includes providing researchers with the necessary computing power and datasets to train artificial intelligence (AI) models.

The mission also intends to build an integrated AI platform to harness Federal scientific datasets for training scientific foundation models and creating AI agents.

The Genesis Mission AI initiative targets several areas identified as “science and technology challenges of national importance” for the application of artificial intelligence.

One application area specifically targeted by the order is advanced manufacturing and robotics.

Other critical application areas specified in the order include biotechnology and nuclear fission and fusion. The executive order mandates that, with increased computing resources and access to data, AI should be applied to these practical and critical scientific issues within 270 days.