Andrea Sturchio, Karolinska Institutet; Kariem Ezzat, Karolinska Institutet, and Samir EL Andaloussi, Karolinska Institutet
In 1906, Alois Alzheimer, a psychiatrist and neuroanatomist, reported “a peculiar severe disease process of the cerebral cortex” to a gathering of psychiatrists in Tübingen, Germany. The case was a 50-year-old woman who suffered from memory loss, delusions, hallucinations, aggression and confusion – all of which worsened until her untimely death five years later.